Fig. 2

Effect of circ_0000517 knockdown on hepatocellular carcinoma progression. a circ_0000517 expression was examined in HCCLM3 and Huh7 cells with transfection of si-circ_0000517#1, #2, #3 or si-NC. Cell viability (b, c), colony formation (d), Ki67 and PCNA protein levels (e), migration (f), invasion (g), E-cadherin and Vimentin protein levels (h), glucose consumption (i), lactate production (j), ATP production (k), and LDHA and HK2 protein levels (l) were detected in HCCLM3 and Huh7 cells transfected with si-circ_0000517#3 or si-NC. ^*P < 0.05