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Fig. 6 | Cancer Cell International

Fig. 6

From: XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way

Fig. 6

XIST overexpression reduced cancer stem cells in vivo and thereby increased the sensitivity of ovarian cancer cells to Taxol treatment. a XIST overexpression impaired tumor volume in ovarian cancer cells. b XIST overexpression improved the role of paclitaxel in the body. c XIST correlated with the percentage of CD44 +  CD24−population in tumors. d KMT2C protein expression in tumors of TOV21G-OE and parental TOV21G.*p < 0.05, **p < 0.01

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