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Fig. 2 | Cancer Cell International

Fig. 2

From: Circ_0000140 restrains the proliferation, metastasis and glycolysis metabolism of oral squamous cell carcinoma through upregulating CDC73 via sponging miR-182-5p

Fig. 2

Effects of circ_0000140 overexpression on the proliferation, migration and invasion of OSCC cells. CAL-27 and SCC-4 cells were transfected with circ_0000140 overexpression vector or vector. a The expression of circ_0000140 in CAL-27 and SCC-4 cells was detected by qRT-PCR to evaluate transfection efficiency. b Colony formation assay was performed to measure the number of colonies in CAL-27 and SCC-4 cells. c, d The number of migrated and invaded CAL-27 and SCC-4 cells was determined by transwell assay. e, f WB analysis was performed to detect the protein levels of ki67, MMP-2 and MMP-9 in CAL-27 and SCC-4 cells. ** P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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