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Fig. 6 | Cancer Cell International

Fig. 6

From: Circ_0000140 restrains the proliferation, metastasis and glycolysis metabolism of oral squamous cell carcinoma through upregulating CDC73 via sponging miR-182-5p

Fig. 6

MiR-182-5p could target CDC73. a The sequences of CDC73 3′UTR containing the miR-182-5p binding sites or mutant binding sites were shown. b, c The interaction between miR-182-5p and CDC73 in CAL-27 and SCC-4 cells was assessed by dual-luciferase reporter assay. d The protein level of CDC73 in OSCC cells (CAL-27 and SCC-4) and HOK cells was determined by WB analysis. e WB analysis was used to measure the CDC73 protein level in CAL-27 and SCC-4 cells to evaluate the miR-182-5p expression on CRC73 expression. f, g The CDC73 protein level in CAL-27 and SCC-4 cells was detected by WB analysis to evaluate the circ_0000140 and miR-182-5p expression on CDC73 expression. ** P < 0.01

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