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Fig. 1 | Cancer Cell International

Fig. 1

From: NNT-AS1 modulates prostate cancer cell proliferation, apoptosis and migration through miR-496/DDIT4 axis

Fig. 1

NNT-AS1 knockdown inhibited PCa cell viability, proliferation, migration and promoted apoptosis. a NNT-AS1 expression was examined using RT-qPCR in PCa cells. b NNT-AS1 expression was detected by RT-qPCR in PCa cells transfected with shRNAs targeting NNT-AS1. c CCK-8 assay indicated cell viability when NNT-AS1 was down-regulated in VCaP and PC3 cells. d, e EdU and colony formation assays measured cell proliferation in VCaP and PC3 cells with or without NNT-AS1 inhibition. f, g Flow cytometry analysis and JC-1 assay examined the apoptosis rate of VCaP and PC3 cells with or without NNT-AS1 silence. h Wound healing assay displayed the migration capacity of VCaP and PC3 cells with silenced NNT-AS1 or not. *p < 0.05, **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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