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Fig. 3 | Cancer Cell International

Fig. 3

From: MicroRNA-214-3p inhibits the stem-like properties of lung squamous cell cancer by targeting YAP1

Fig. 3

miR-214-3p impairs tumorigenicity of LSCC in vivo and activates the Hippo pathway decreases YAP1 protein level. a and b H520 and HCC95 cells transfected with miR-214-3p were injected into nude mice. c and e Tumor weight and tumor volume were analyzed in H520 cells. d and f Tumor weight and tumor volume were analyzed in HCC95 cells. g and h Fluorescence confocal microscope analysis demonstrated miR-214-3p overexpression decreased YAP1 levels of mice tumors. i Protein levels of Hippo components, after transfected with miR-214-3p in H520 cells. (At first, 7 mice models were established in each group, but 2 mice died in HCC95 groups).*p < 0.05, **p < 0.01, ***p < 0.001

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