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Table 1 Study characteristics and quality assessment of all the included studies for biomarkers

From: Clinical implication of prognostic and predictive biomarkers for castration-resistant prostate cancer: a systematic review

Article Year No of patients Study type Quality assessmenta
Yasouka et al. [48] 2019 44 Observational 4
Lin et al. [53] 2018 216 Observational 6
Kosaka et al. [49] 2018 45 Observational 3
Pei et al. [51] 2019 170 Observational 4
Sathekge et al. [60] 2019 73 Observational 2
Alvim et al. [63] 2019 124 Observational 6
Armstrong et al. [70] 2018 872 Observational 4
Hamano et al. [57] 2019 321 Observational 6
Yang et al. [52] 2015 39 Observational 4
Houede et al. [65] 2015 306 Observational 4
Kuo et al. [56] 2015 62 Observational 5
Schiff et al. [64] 2019 110 Observational 3
Rahbar et al. [61] 2017 104 Observational 4
Ahmadzadehfar et al. [62] 2017 100 Observational 4
Ji et al. [54] 2017 185 Observational 4
He et al. [55] 2017 92 Observational 4
Belderbos et al. [50] 2019 224 Observational 4
Chang et al. [66] 2019 77 Observational 5
Fan et al. [67] 2018 60 Observational 7
Fukuoka et al. [58] 2019 63 Observational 4
Kodama et al. [87] 2019 575 Observational 6
Papazoglou et al. [69] 2016 44 Observational 4
Miyake et al. [68] 2017 297 Observational 4
Vaishampayan et al. [29] 2019 20 Observational 4
Dizdarevic et al. [32] 2018 57 Observational 4
Naito et al. [31] 2019 20 Observational 3
Miyoshi et al. [33] 2019 32 Observational 4
Lara et al. [30] 2018 750 RCT 4
Hammerrich et al. [34] 2017 89 Observational 5
Anand et al. [35] 2016 62 Observational 5
Onal et al. [36] 2019 102 Observational 6
Loubersac et al. [37] 2019 1082 RCT 3
Tatenuma et al. [38] 2018 73 Observational 4
Kumano et al. [39] 2019 106 Observational 4
Lorente et al. [40] 2015 755 RCT 2
Koo et al. [41] 2019 303 Observational 6
Ando et al. [44] 2019 164 Observational 5
Hashimoto et al. [45] 2019 115 Observational 6
Shiota et al. [46] 2018 106 Observational 4
Wang et al. [47] 2017 206 Observational 6
Sieuwerts et al. [18] 209 124 Observational 4
Belderbos et al. [19] 2019 127 Observational 4
Cattrini et al. [20] 2019 39 Observational 4
Qu et al. [21] 2014 250 Observational 6
Antonarakis et al. [22] 2017 202 Observational 5
Qu et al. [23] 2017 171 Observational 6
Carles et al. [24] 2018 45 Observational 5
De Kruihiff et al. [25] 2019 114 Observational 4
Bitting et al. [26] 2015 89 Observational 4
Josefsson et al. [27] 2017 53 Observational 5
Kobayashi et al. [71] 2019 104 Observational 6
Hiew et al. [72] 2018 270 Observational 3
Gravis et al. [73] 2015 385 Observational 4
Mori et al. [74] 2017 69 Observational 4
Miyoshi et al. [75] 2018 45 Observational 4
Ohtaka et al. [76] 2017 49 Observational 4
Song et al. [42] 2016 71 Observational 5
Berg et al. [43] 2015 194 Observational 5
  1. a Quality assessment of the RCTs were done using Jadad scale and non-RCTs was done using Newcastle–Ottawa scale
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