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Fig. 3 | Cancer Cell International

Fig. 3

From: Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway

Fig. 3

TRIB3-siRNA inhibited invasion, migration and epithelial mesenchymal transition (EMT) of ovarian cancer cells. a TRIB3-siRNA suppressed invasion of ovarian cancer cells (×200). b TRIB3-siRNA inhibited migration of ovarian cancer cells (×100). c Transfection of TRIB3 siRNA decreased the expression of MMP2, MMP9, E-cadherin, N-cadherin, Vimentin, Twist protein. GAPDH was used as an internal control. d Immunocytochemical staining of TRIB3, E-cadherin, N-cadherin, Twist in OVCAR3 cell. Data are presented as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001

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