Fig. 4
From: Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway
The mechanisms of TRIB3 function in ovarian cancer. a The bubble plot of top 20 biological functions and pathways related to TRIB3. b GSEA analysis of TRIB3-reated enrichment gene sets. c Western blot analysis showed that the expression of MEK, p-MEK, ERK, p-ERK protein in ovarian cancer cells decreased after transfection with TRIB3-siRNA. GAPDH was used as an internal control. d The gene interaction network of top 20 genes related to TRIB3 in Genemania. e TRIB3 genetic variation analysis in cBioPortal. f Survival analysis of TRIB3 genetic variation in cBioPortal. g, h The relationship between TRIB3 and immune sub-types or molecular sub-types in the TISIDB database. Data are presented as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001