Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway

Table 4 Univariate and multivariate cox analysis of different clinicopathological parameters with ovarian cancer

Variable	Categories	Univariate analysis		P	Multivariate analysis		P
Variable	Categories	HR	95% CI	P	HR	95% CI	P
Age	≤ 54	1.891	(0.911–3.926)	0.087
Age	> 54	1.891	(0.911–3.926)	0.087
Differentiation	Well-moderate	1.712	(0.838–3.496)	0.094
Differentiation	Poor	1.712	(0.838–3.496)	0.094
FIGO stage	I–II	4.980	(1.907–13.005)	0.001**	3.403	(1.119–10.346)	0.031^*
FIGO stage	III–IV	4.980	(1.907–13.005)	0.001**	3.403	(1.119–10.346)	0.031^*
Lymph node metastasis	No	2.817	(1.300–6.105)	0.009**	1.466	(0.619–3.471)	0.384
Lymph node metastasis	Yes	2.817	(1.300–6.105)	0.009**	1.466	(0.619–3.471)	0.384
TRIB3	Low	2.194	(1.068–4.507)	0.032*	1.517	(0.682–3.374)	0.306
TRIB3	High	2.194	(1.068–4.507)	0.032*	1.517	(0.682–3.374)	0.306

ISSN: 1475-2867