Skip to main content
Fig. 7 | Cancer Cell International

Fig. 7

From: MiR-924 as a tumor suppressor inhibits non-small cell lung cancer by inhibiting RHBDD1/Wnt/β-catenin signaling pathway

Fig. 7

MiR-924 inhibited tumor growth of NSCLC in vivo by targeting RHBDD1 via deactivation of the Wnt/β-catenin pathway. a Representative images of xenograft tumors excised from nude mice derived 30 days after subcutaneous inoculation of H1299 cells transfected with miR-924 mimic or miR-NC. b The volume of tumor xenografts was measured every 5 days. The growth of the tumor xenografts in the miR-924 mimic group was notably slower than that in the miR-NC group. c All nude mice were sacrificed 30 days after injection, and the tumor xenografts were excised. The weight of the tumor xenografts in the miR-924 mimic group was notably lower than that in the miR-NC group. d The protein levels of RHBDD1, Wnt1, β-catenin, GSK-3β and p-GSK-3β in xenografts were examined using western blot. **p < 0.01, compared with miR-NC

Back to article page