Fig. 4From: The relationship between TRAF6 and tumorsThe mechanism for regulation of TRAF6. At present, the expression of TRAF6 is mainly affected by the E3 ubiquitin ligase (Parkin and CHIP) and miRNAs (miR-146a-5p, miR-146b-5p, miR-643 and miR–124). The ubiquitin ligase activity of TRAF6 is mainly affected by deubiquitinating enzymes (A20, CYLD and USP25) and BidBack to article page