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Fig. 2 | Cancer Cell International

Fig. 2

From: circRAE1 promotes colorectal cancer cell migration and invasion by modulating miR-338-3p/TYRO3 axis

Fig. 2

Function of CircRAE1 in CRC cells. a Expression of CircRAE1 after transfection with various siRNAs and negative control for 48 h in SW620 and HT29 cells as detected by qRT-PCR. b, c Downregulation of CircRAE1-suppressed SW620 and HT29 cell proliferation ability as determined by CCK8 and colony formation assays. d Downregulation of CircRAE1-suppressed SW620 and HT29 cell migration ability as determined by wound healing tests. e Downregulation of CircRAE1-suppressed SW620 and HT29 cell migration and invasion ability as determined by Transwell assays. f Expression of E-cadherin and vimentin in SW620 and HT29 as detected by qRT-PCR after transfection with si-circRAE1 or si-NC. g Protein level of E-cadherin and vimentin in SW620 and HT29 as detected by Western blot assay. *P < 0.05, **P < 0.01, ***P < 0.001

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