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Fig. 3 | Cancer Cell International

Fig. 3

From: Circ_0004913 sponges miR-1290 and regulates FOXC1 to inhibit the proliferation of hepatocellular carcinoma

Fig. 3

miR-1290 acted as the target of circ_0004913. Bioinformatics tools indicated the complementary binding sites of miR‐1290 with circ_0004913. b Luciferase reporter assay showed the targeting of miR‐1290 with circ_0004913 in HEK293T. c RIP and qRT-PCR assays measured the expression differences in circ_0004913 and miR-1290 between the Ago2 immunoprecipitation and the IgG immunoprecipitation. d qRT‐PCR showed the miR-1290 expression after circ_0004913 overexpression. e Relative miR-1290 expression in HCC tissues and adjacent tissues. f The correlation between miR‐605 and circFBXO11 was calculated by Spearman’s rank correlation coefficients. g Relative miR-1290 expression in HCC cells and L02. Data (n = 5) are the means ± SD. *P  < 0.05, **P < 0.01, ***P <  0.001

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