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Fig. 6 | Cancer Cell International

Fig. 6

From: Circ_0004913 sponges miR-1290 and regulates FOXC1 to inhibit the proliferation of hepatocellular carcinoma

Fig. 6

circ_0004913 suppressed the proliferation of HCC cells in vivo. a Tumor volume was calculated with length × width2/2 method at the indicated time point. b The image of xenograft tumor in control or circ-1,004,913 group (n = 3/group, Scale bar = 1 cm). c Tumor weight was measured in mice. d The expression level of circ_1004913 was detected by qRT-PCR. e The protein levels of PCNA and FOXC1 were tested by WB analysis. f, g qRT-PCR analysis of miR-1290 and FOXC1 expression in nude mice bearing xenograft tumor with or without circ_0004913 overexpression. Data (n = 5) are the means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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