Fig. 1

Identification of lncRNA targets of KLF5 in CRC. a This represents the computational pipeline for identifying the lncRNA targets of KLF5 in CRC. b The visualization of the KLF5 lncRNA target network. The central node is KLF5. Other nodes are lncRNA targets of KLF5. c The enriched GO BP terms of the KLF5 targets that were up-regulated in CRC demonstrated that its major functions are involved with cell cycle, DNA repair, and DNA replication. d The three motif patterns of the KLF5 binding sites on the lncRNAs (with most occurrences) are presented in MEME software. e The enriched GO BP terms of the KLF5 targets that were down-regulated in CRC showing that the functions are related to signal transduction