Fig. 1
From: MicroRNA-585 inhibits human glioma cell proliferation by directly targeting MDM2
miR-585 is downregulated in human glioma tissues and cell lines. a qRT-PCR analysis of miR-585 expression in human glioma tissues (grade I + II, n = 15; grade III + IV, n = 18) and paired surrounding normal brain tissues (NB). Results are normalized to that of U6 snRNA internal control. Data are mean ± SD. Statistical analysis was performed by two-tailed Student’s t test for paired (**P < 0.01) and unpaired (#P < 0.01) data. b qRT-PCR analysis of miR-585 expression in 4 different human glioma cell lines as indicated. The normal brain (NB) total RNA was used as a control. Results are normalized to that of U6 snRNA and expressed as a fold change against NB. Data are mean ± SD (n = 3). Two-tailed unpaired Student’s t-test. **P < 0.01 (vs. NB)