Fig. 8

Overexpression of miR-221-3p enhances the drug resistance of PC cells. a The inhibitory effect of gemcitabine at a series of concentrations on cytoactivity (green: treated with control mimic; purple: treated with miR-221-3p mimic. b The inhibitory effect of gemcitabine at a series of concentrations on cytoactivity (green: treated with control inhibitor; purple: treated with miR-221-3p inhibitor). c The inhibitory effect of gemcitabine at a series of concentrations on cytoactivity (green: treated with control mimic; purple: treated with miR-221-3p mimic). d The inhibitory effect of gemcitabine at a series of concentrations on cytoactivity (green: treated with control inhibitor; purple: treated with miR-221-3p inhibitor). The findings were assessed with t tests (unpaired). Five replications were performed for each experiment