MicroRNA-221-3p is related to survival and promotes tumour progression in pancreatic cancer: a comprehensive study on functions and clinicopathological value

Table 1 Relationship between clinical features of pancreatic cancer and the miR-221-3p content in TCGA dataset

Characteristics	N	M ± SD	p
Tissues
Adjacent non-cancerous tissues	4	9.728 ± 0.6995	0.1568
Pancreatic cancer	179	10.50 ± 1.073
Age (years)
< 60	55	10.85 ± 1.010	0.0027*
≥ 60	124	10.34 ± 1.066
Gender
Male	99	1.172	0.8089
Female	80	0.9425
Radiation therapy
No	120	10.48 ± 1.147	0.7639
Yes	44	10.54 ± 0.9448
Smoking status
No	120	10.57 ± 0.9689	0.1918
Yes	59	10.35 ± 1.254
Tumour location
Pancreas	178	10.49 ± 1.076	0.0193*
Metastasis	1	10.685
Vital status
Alive	86	10.36 ± 1.167	0.0989
Dead	93	10.62 ± 0.9674
Stage
Stage I–II	168	10.49 ± 1.083	0.9691
Stage III–IV	9	10.48 ± 0.7458
T
T1-T2	32	10.63 ± 1.321	0.4649
T3-T4	146	10.47 ± 1.015
N
No	124	10.47 ± 1.023	0.7403
Yes	54	10.53 ± 1.185
M
No	174	10.50 ± 1.083	0.8312
Yes	5	10.39 ± 0.6852
Residual tumour
No	111	10.44 ± 1.194	0.389
Yes	58	10.59 ± 0.8653

N indicates number, SD indicates standard deviation, M indicates mean, *indicates significant difference defined as p < 0.05

ISSN: 1475-2867