Table 2 Relationship between clinical features of pancreatic cancer and the miR-221-3p content determined by RT-qPCR
Characteristics | N | M ± SD | p |
|---|---|---|---|
Tissues | |||
 Adjacent non-cancerous tissues | 16 | 9.603 ± 1.129 | < 0.0001* |
 Pancreatic cancer | 16 | 12.422 ± 1.147 |  |
Age (years) | |||
 < 60 | 5 | 12.87 ± 1.040 | 0.3038 |
 ≥ 60 | 11 | 12.22 ± 1.179 |  |
Gender | |||
 Male | 8 | 12.40 ± 1.202 | 0.9533 |
 Female | 8 | 12.44 ± 1.172 |  |
Tumor size(cm) | |||
 ≤3 | 6 | 12.10 ± 0.902 | 0.4093 |
 >3 | 10 | 12.61 ± 1.278 |  |
smoke | |||
 No | 11 | 12.58 ± 1.217 | 0.4346 |
 Yes | 5 | 12.08 ± 1.007 |  |
Lymphatic Metastasis | |||
 No | 7 | 12.06 ± 1.070 | 0.2834 |
 Yes | 9 | 12.70 ± 1.186 |  |
Vital status | |||
 Live | 3 | 11.61 ± 0.037 | 0.1832 |
 Death | 13 | 12.61 ± 1.201 |  |
Stage | |||
 Stage I–II | 8 | 12.81 ± 1.337 | 0.1836 |
 Stage III–IV | 8 | 12.03 ± ±0.827 |  |
Vascular invasion | |||
 No | 5 | 12.77 ± 1.360 | 0.4338 |
 Yes | 11 | 12.26 ± 1.070 |  |
Histological type | |||
 Pancreatic ductal adenocarcinoma | 15 | 12.482 ± 1.160 | 0.0061* |
 Undifferentiated cancer | 1 | 11.516 |  |
Nerve invasion | |||
 No | 2 | 12.92 ± 1.905 | 0.528 |
 Yes | 14 | 12.35 ± 1.093 |  |
Diabetes | |||
 No | 13 | 12.04 ± 0.850 | 0.0016* |
 Yes | 3 | 14.09 ± 0.617 |  |