Fig. 5

LINC02418 indirectly regulated BCL2 expression through sponging miR-34b-5p. a Endogenous protein level of BCL2, caspase 9, caspase 3 and cleaved-caspase 9, cleaved-caspase 3 were detected in HCT116 and LoVo cells by western blotting. b, c Cell growth of HCT116 and LoVo cells were determined by CCK-8 assays and colony formation assays. d Apoptosis rates of HCT116 and LoVo cells were analyzed by flow cytometry assays. Each independent experiment contained 3 repeated samples per group. The error bars stand for standard deviation (SD). Data were representatives of three independent experiments with similar results; **P < 0.01, compared to sh-NC group; ^{^^}P < 0.01, compared to sh-LINC02418 group