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Table 1 Correlation of RUNX3 mRNA expression with the clinicopathological factors of esophageal cancer patients

From: Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India

Clinicopathological parameters

No. of patients

RUNX3 expression relative to β-Actin

p-value

Age

   

 ≥ 50

44

4.26 ± 4.9

0.351

 < 50

13

5.28 ± 5.4

 

Sex

   

 Male

32

5.34 ± 4.4

0.711

 Female

25

4.68 ± 6.4

 

TNM Classification

   

 Locally advanced resectable

28

5.05 ± 5.8

 

 Locally advanced unresectable

25

5.04 ± 5.2

0.728

 Metastatic

4

5.13 ± 2.8

 

Dysphagia Grade

   

 dys Gr1

1

4.09 ± 0

 

 dys Gr2

19

5.25 ± 5.8

 

 dys Gr3

24

4.92 ± 5.2

0.359

 dys Gr4

11

6.48 ± 3.1

 

 dys Gr5

2

-2.6 ± 9.05

 

Location of Tumor

   

 Upper third

7

7.88 ± 3.1

 

 Middle third

25

4.78 ± 4.6

0.272

 Lower third

25

4.53 ± 6.2

 

Smoking

   

 Smoker

32

5.46 ± 4.7

0.742

 Non-smoker

25

4.53 ± 6.04

 

Alcohol

   

Alcoholic

21

5.5 ± 3.7

0.967

 Non-Alcoholic

36

4.79 ± 6.1

 

 Tobacco

   

 Tobacco Chewer

5

7.62 ± 4.1

0.438

 Non-Tobacco Chewer

52

4.81 ± 5.4

 

Type

   

 SCC

51

5.12 ± 5.5

0.153

 Adeno

6

4.45 ± 2.6

 

Diet

   

 Non Veg

31

5.39 ± 4.1

0.866

 Veg

26

4.77 ± 6.2

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