Table 1 Correlation of RUNX3 mRNA expression with the clinicopathological factors of esophageal cancer patients
From: Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India
| Clinicopathological parameters | No. of patients | RUNX3 expression relative to β-Actin | p-value |
|---|---|---|---|
| Age | |||
| ≥ 50 | 44 | 4.26 ± 4.9 | 0.351 |
| < 50 | 13 | 5.28 ± 5.4 | |
| Sex | |||
| Male | 32 | 5.34 ± 4.4 | 0.711 |
| Female | 25 | 4.68 ± 6.4 | |
| TNM Classification | |||
| Locally advanced resectable | 28 | 5.05 ± 5.8 | |
| Locally advanced unresectable | 25 | 5.04 ± 5.2 | 0.728 |
| Metastatic | 4 | 5.13 ± 2.8 | |
| Dysphagia Grade | |||
| dys Gr1 | 1 | 4.09 ± 0 | |
| dys Gr2 | 19 | 5.25 ± 5.8 | |
| dys Gr3 | 24 | 4.92 ± 5.2 | 0.359 |
| dys Gr4 | 11 | 6.48 ± 3.1 | |
| dys Gr5 | 2 | -2.6 ± 9.05 | |
| Location of Tumor | |||
| Upper third | 7 | 7.88 ± 3.1 | |
| Middle third | 25 | 4.78 ± 4.6 | 0.272 |
| Lower third | 25 | 4.53 ± 6.2 | |
| Smoking | |||
| Smoker | 32 | 5.46 ± 4.7 | 0.742 |
| Non-smoker | 25 | 4.53 ± 6.04 | |
| Alcohol | |||
| Alcoholic | 21 | 5.5 ± 3.7 | 0.967 |
| Non-Alcoholic | 36 | 4.79 ± 6.1 | |
| Tobacco | |||
| Tobacco Chewer | 5 | 7.62 ± 4.1 | 0.438 |
| Non-Tobacco Chewer | 52 | 4.81 ± 5.4 | |
| Type | |||
| SCC | 51 | 5.12 ± 5.5 | 0.153 |
| Adeno | 6 | 4.45 ± 2.6 | |
| Diet | |||
| Non Veg | 31 | 5.39 ± 4.1 | 0.866 |
| Veg | 26 | 4.77 ± 6.2 |
