Table 3 Correlation of EZH2 mRNA expression with the clinicopathological factors of esophageal carcinoma patients
From: Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India
| Clinicopathological parameters | No. of patients | EZH2 expression relative to β-Actin | p-value |
|---|---|---|---|
| Age | |||
| ≥ 50 | 40 | 6.53 ± 1.4 | 0.595 |
| < 50 | 12 | 6.61 ± 1.9 | |
| Sex | |||
| Male | 31 | 6.47 ± 1.4 | 0.751 |
| Female | 21 | 6.66 ± 1.6 | |
| Classification | |||
| Locally advanced resectable | 25 | 6.59 ± 1.5 | |
| Locally advanced unresectable | 23 | 6.63 ± 1.6 | 0.532 |
| Metastatic | 4 | 5.79 ± 1.1 | |
| Dysphagia Grade | |||
| dys Gr1 | 1 | 6.34 ± 0 | |
| dys Gr2 | 18 | 6.31 ± 1.5 | |
| dys Gr3 | 21 | 6.96 ± 1.5 | 0.314 |
| dys Gr4 | 11 | 6.41 ± 1.2 | |
| dys Gr5 | 1 | 3.83 ± 0 | |
| Location of Tumor | |||
| Upper third | 7 | 6.28 ± 1.9 | |
| Middle third | 24 | 6.67 ± 1.6 | 0.799 |
| Lower third | 21 | 6.51 ± 1.2 | |
| Smoking | |||
| Smoker | 30 | 6.51 ± 1.3 | 0.803 |
| Non-smoker | 22 | 6.60 ± 1.7 | |
| Alcohol | |||
| Alcoholic | 20 | 6.58 ± 1.6 | 0.94 |
| Non-Alcoholic | 32 | 6.53 ± 1.5 | |
| Tobacco | |||
| Tobacco Chewer | 5 | 6.32 ± 1.2 | 0.78 |
| Non-Tobacco Chewer | 47 | 6.57 ± 1.5 | |
| Type | |||
| SCC | 47 | 6.58 ± 1.5 | 0.609 |
| Adeno | 5 | 6.19 ± 0.8 | |
| Diet | |||
| Veg | 28 | 6.33 ± 1.3 | 0.233 |
| NonVeg | 24 | 6.80 ± 1.6 |
