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Fig. 3 | Cancer Cell International

Fig. 3

From: Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia

Fig. 3

AP2M1 knockdown reverses the inhibitory effects of ALT on ALL cell proliferation. BV173 and NALM6 cells were transfected with si-AP2M1 or si-NC, and then treated with 5 μM of ALT for 24 h. a qPCR was performed to evaluate the expression of AP2M1. b MTT assays were used to assess cell proliferation. c Colony formation assays were performed to investigate the colony formation ability of ALL cells. *P < 0.05. siRNA, small interfering RNA; AP2M1, adaptor related protein complex 2 subunit mu 1; ALL, acute lymphoblastic leukemia; ALT, alantolactone

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Cancer Cell International

ISSN: 1475-2867

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