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Fig. 3 | Cancer Cell International

Fig. 3

From: HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway

Fig. 3

HKDC1 promoted proliferation, invasion, migration in vitro and tumorigenesis in vivo. a, b The mRNA (a) and protein levels (b) of HKDC1 were detected after transfection with overexpressed HKDC1 in both A549 and H1299 cells. c The viability of LUAD cells with HKDC1 overexpression was increased by CCK-8 assay. d, e Overexpression of HKDC1 promoted A549 (d) and H1299 (e) cells migration and invasion in vitro as assessed by the wound healing assay (scale bar, 100 μm). f HKDC1 overexpression promoted tumor growth in vivo. Data were expressed as the mean ± standard deviation (mean ± SD) *p < 0.05, **p < 0.01

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