Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: RUNX2 interacts with BRG1 to target CD44 for promoting invasion and migration of colorectal cancer cells

Fig. 2

RUNX2 promotes CD44-induced EMT in CRC cells. a, c The number of invading cells was determined by using the transwell assay in RKO and HT115 cells. b, d The wound healing rate of RKO and HT115 cells was measured by the wound healing assay. e Knockdown of RUNX2 promoted E-cadherin expression and inhibited N-cadherin expression in RKO cells. f Overexpression of RUNX2 inhibited E-cadherin expression and promoted N-cadherin expression in HT115 cells. g Knockdown of CD44 increased E-cadherin expression and decreased N-cadherin expression in RUNX2-overexpressed HT115 cells. Data are shown as means ± SE; *P<0.05, **P<0.01; NC negative control, si short interfering, RUNX2 overexpression of RUNX2

Back to article page