Fig. 1From: The Ibr-7 derivative of ibrutinib radiosensitizes pancreatic cancer cells by downregulating p-EGFRIbr-7 showed potent anti-proliferative activity against pancreatic cancer cells in dose-dependent manner. a The chemical structure of ibrutinib (Ibr) and Ibr-7. b CCK8 assay was performed to detect the inhibitory activity of ibrutinib (Ibr) or Ibr-7 on the proliferation on pancreatic cancer cell line PANC-1, Capan2 cell lines for 48 h in vitro. Three independent experiments were performed and data were presented as mean ± SD (standard deviation)Back to article page