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Fig. 5 | Cancer Cell International

Fig. 5

From: The Ibr-7 derivative of ibrutinib radiosensitizes pancreatic cancer cells by downregulating p-EGFR

Fig. 5

Ibr-7 increased radiation induced DNA double-strand breaks. a The representative images of γ-H2AX foci immunofluorescence staining in PANC-1 and Capan2 cells treated with 6 Gy radiation with or without Ibr-7 at 24 h after radiation. b Cells with γ-H2AX foci were counted and quantified. Error bars indicated SE. Significance was determined by Student’s t-test. Scale bar = 10 μm. (**p < 0.01, ***p < 0.001 compared with combination group)

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