Table 2 Review for the regulatory roles of selected differentially co-expressed genes on cancer cells

CEACAM1

chr19

Up

Modulating GC invasiveness, lumen formation, growth and metastasis

[38, 39]

ATP10B

chr5

Up

Unknown

FUT6

chr19

Up

Promoting CRC and BC cell proliferation, migration and invasion

[40, 41]

PSG8

chr19

Up

Unknown

ARHGAP11A

chr15

Up

Facilitating HCC cell proliferation, invasion, migration and EMT; Promoting BLBC growth

[42,43,44]

C5orf34

chr5

Up

Unknown

FAM151B

chr5

Up

Facilitating LAD cell proliferation and migration

[45]

CHEK2

chr22

Up

Promoting GC cell proliferation

[46,47,48]

AIMP2

chr7

Up

Suppressing cell apoptosis of lung cancer and EOC

[49,50,51]

RAD51D

chr17

Up

Increasing BC cell growth

[52]

POF1B

chrX

Up

Unknown

PPA1

chr10

Up

Promoting cell proliferation and inhibiting apoptosis of NSCLC, ovarian cancer and colon cancer

[53,54,55,56]

S100A3

chr1

Up

Suppressing cell apoptosis and increasing invasion of CRPC

[57]

PCNA

chr20

Up

Cell proliferation marker

[58, 59]

MYBL2

chr20

Up

Regulating cell proliferation, survival and differentiation

[60, 61]

CD276

chr15

Up

Promoting GC cell migration and invasion

[62, 63]

PGA3

chr11

Down

Unknown

GIF

chr11

Down

Gastric intrinsic factor

[64, 65]

GPER1

chr7

Down

Increasing GC cell apoptosis

[66]

FGA

chr4

Down

Inhibiting LAD cell proliferation, migration and invasion

[67]

SYNE1

chr6

Down

Unknown

GNMT

chr6

Down

Promoting cell proliferation and regulating apoptosis of PC; Reducing HCC cell proliferation;

[68,69,70]

MACROD2

chr20

Down

Inhibiting HCC cell proliferation, invasiveness and EMT

[71]

PCDH11Y

chrY

Down

Unknown

C1QTNF9

chr13

Down

Unknown

S100B

chr21

Down

Inhibiting GC cell growth and invasion

[72]

ADAMTSL1

chr9

Down

Regulating chondrosarcoma cell proliferation

[73]

CADM2

chr3

Down

Inhibiting cell proliferation, migration, invasion and inducing apoptosis of various cancer

[74,75,76,77,78,79]

PAPPA2

chr1

Down

Unknown