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Table 3 Relationship between the level of ADAM17 and active MMP21 and variable Clinicpathological features (Chi-square test)

From: ADAM17 promotes the invasion of hepatocellular carcinoma via upregulation MMP21

Tissues n ADAM17 expression High expression rate (%) P
Low expression High expression
Gender
 Male 54 4 50 92.59 0.849
 Female 11 1 10 90.90  
Age (year)
 > 50 30 1 29 96.67 0.222
 ≤ 50 35 4 31 88.57  
Tumor number
 Single 52 5 47 90.38 0.574
 Multiple 13 0 13 100  
Tumor size (cm)
 ≤ 3 12 0 12 100 0.575
 > 3 53 5 48 90.57  
Histology
 Well 4 1 3 75 0.346
 Moderately 43 2 41 95.35  
 Moderately-Poor 13 1 12 92.31  
 Poor 5 1 4 80  
Microvascular invasion
 Yes 38 1 37 97.37 0.069
 No 27 4 23 85.19  
Tissues n MMP21 expression High expression rate (%) P
Low expression High expression
Gender
 Male 54 5 49 90.74 0.384
 Female 1 2 9 81.82  
Age(year)
  > 50 30 3 27 90 0.853
  ≤ 50 35 4 31 88.57  
Tumor number
 Single 52 5 47 90.38 0.548
 Multiple 13 2 11 84.62  
Tumor size (cm)
 ≤ 3 12 2 10 83.33 0.604
 > 3 53 5 48 90.57  
Histology
 Well 4 1 3 75 0.171
 Moderately 43 2 41 95.35  
 Moderately- Poor 13 3 10 76.92  
 Poor 5 1 4 80  
Microvascular invasion
 Yes 41 1 40 97.56 0.005
 No 24 6 18 75