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Fig. 5 | Cancer Cell International

Fig. 5

From: Promotion of BZW2 by LINC00174 through miR-4500 inhibition enhances proliferation and apoptosis evasion in laryngeal papilloma

Fig. 5

LINC00174/miR-4500/BZW2 axis regulated cell proliferation and apoptosis. The LP cells were co-transfected with si-NC plus miRNA negative control (NC)-inhibitor), LINC00174-1 siRNA plus miRNA NC-inhibitor, or LINC00174-1 siRNA plus miR-4500 inhibitor. a, b qRT-PCR and western blotting were used to determine the mRNA and protein levels of BZW2. c, d CCK-8 and colony formation assays were used to evaluate cell proliferation. e, f Nucleosomal fragmentation and caspase-3 activity assays were used to assess cell apoptosis in each group. The data represented are the means ± S.D. *P < 0.05, **P < 0.01, *** P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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