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Table 2 Univariable and multivariable Cox regression analysis for prediction of RFS in GSE27020 dataset

From: Identification and validation of methylation-driven genes prognostic signature for recurrence of laryngeal squamous cell carcinoma by integrated bioinformatics analysis

Factors Subgroup Univariable analysis Multivariable analysis
HR (95% CI) P HR (95% CI) P
Age   1.02(0.99–1.06) 0.193 NA NA
Sex Female 1    
  Male 21.94(0.34–32.16) 0.377 NA NA
Smoking history No 1    
  Yes 20.53(0.06–28.44) 0.679 NA NA
Alcohol history No 1    
  Yes 1.17 (0.58–2.33) 0.664 NA NA
Tumor grade G1–G2 1    
  G3–G4 0.90(0.64–1.26) 0.998 NA NA
Clinical stage I–II 1    
  III-IV 1.00(0.61–1.65) 0.525 NA NA
Radiation therapy Yes    NA NA
  No 2.22(0.98–4.99) 0.055 NA NA
MDGPS   1.15(1.09–1.22) 0.000* 1.17(1.09–1.24) 0.000*
  1. HR hazard ratio, CI confidence intervals, RFS recurrence-free survival, NA not available
  2. These variables were eliminated in the multivariate cox regression model, so the HR and P values were not available.*P < 0.05