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Fig. 2 | Cancer Cell International

Fig. 2

From: Aging-related tumor associated fibroblasts changes could worsen the prognosis of GBM patients

Fig. 2

Epidemiology analysis in SEER database presented a clear correlation between age and incidence of GBM. a The incidence of GBM patients in SEER database showed a specific age-related distribution character. The grouped histogram showed the incidence from 18 to 101 years old in SEER database, with the interval of 5 years (18–20, 20–25, 25–30, 30–35, 35–40, 40–45, ……, −100 +). From age of 18–35, the incidence of GBM patients increased slightly with age from 18 to 35, while the trend dramatically increased at the age from 35 to 40 years old. b Ratio chart presented the incidence of male and female patients among different ages. Male patients accounted for a relatively larger proportion of the total number of incidence in all age groups from 18 to 80 years old, but the proportion gradually decreases with age, and after 80 years old, the ratio of men to women is close to 1:1, and even more women patients over 80 years old were involved than men. c, d Ratio chart and line chart showed the tumor-site distribution characters among patients with different ages

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