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Fig. 7 | Cancer Cell International

Fig. 7

From: Aging-related tumor associated fibroblasts changes could worsen the prognosis of GBM patients

Fig. 7

The level of fibroblasts were positively correlated with EMT. ac The evaluation of the accuracy of EMT scores. ROC curve showed the estimation value of EMT score on the diagnosis of mesenchymal and non-mesenchymal subtypes. AUC = 0.862; The correlation between different method calculating the level of EMT. Kaplan–Meier curve showed patients with higher EMT score (showed in green) had worse outcome than those with lower EMT score (showed in yellow). Log-rank test was used as statistical method. P < 0.0001. e Data from different databases all showed the consistent positive correlation between fibroblast and EMT scores. Spearman test was used as statistical method. r = 0.81, 0.88, 0.61 and 0.78 in TCGA, CGGA array, CGGA RNAseq and CGGA RNAseq (recurrent GBM, rGBM), respectively

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