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Fig. 5 | Cancer Cell International

Fig. 5

From: Long non-coding RNA MIR100HG promotes the migration, invasion and proliferation of triple-negative breast cancer cells by targeting the miR-5590-3p/OTX1 axis

Fig. 5

MiR-5590-3p inhibits the invasion and migration of TNBC cells through downregulation of OTX1 expressiona The mRNA level of OTX1 in TNBC cells after OTX1 overexpression, as assessed by RT-qPCR. b, c The level of OTX1 protein expression in TNBC cells after OTX1 overexpression, as assessed by western blot analysis. C is a grayscale analysis chart of B western blot band. The protein level is normalized by β-actin, and then significant difference analysis is performed between OE-OTX1-1, OE-OTX1-2 and vector group. d, e The migration capacity of TNBC cells, as assessed by wound healing assays. Scale bar: 500 µm. f, g The invasive capacity of TNBC cells, as assessed by transwell assays. Scale bar: 100 µm. *P < 0.05, **P < 0.01, ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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