Fig. 5

Correlation of hypoxia signatures and the expression of IGSF9. a Kaplan–Meier survival plots of three hypoxia signatures, these three signatures were related with prognosis in NPC. b Correlation of the scores of three hypoxia signatures and the expression of IGSF9. c Comparison results of the expression level of IGSF9 between high and low groups according to the scores of three hypoxia signatures from the data set GSE102349. Patients used in above analysis (a–c) grouped by the median score of those signatures. d Venn diagram of genes of three hypoxia signatures.e Kaplan–Meier survival plots of P4HA1, which is significantly associated with PFS in NPC. Patients were grouped by the trichotomization (Q1 vs Q4) of P4HA1. f Correlation between  the expression level of P4HA1and IGSF9. g Comparison of the expression level of IGSF9 between low-exp and high-exp group of P4HA1 of the data set GSE102349. Patients used in above analysis (f, g) were grouped by the median value of P4HA1. *P < 0.05, **P < 0.01, ****P < 0.0001