Identification of PKP 2/3 as potential biomarkers of ovarian cancer based on bioinformatics and experiments

Table 2 Expression of PKP2 in different ovarian tissues

Groups	Cases	Low		High		Positive rate (%)	High expression rate (%)
Groups	Cases	−	+	+ +	+ + +	Positive rate (%)	High expression rate (%)
Malignant	117	19	25	48	25	83.8^a,b,c	62.4^d,e,f
Borderline	23	13	2	4	4	43.5	34.8^g
Benign	15	11	1	1	2	26.7	20.0
Normal	15	12	1	2	0	20.0	13.3

^a,b,cIndicated that the positive expression rate of PKP2 in malignant tissues was compared with that in borderline group, benign group and normal tissues, all P<0.05 (P_a<0.001, P_b<0.001, P_c<0.001); ^d,e,fIndicated that the high positive rate of PKP2 in malignant tissues is higher than that in borderline group, benign group and normal tissues, all P<0.05 (P_d = 0.014, P_e = 002, P_e<0.001); ^gIndicated that the high positive expression rate of PKP2 in borderline tissues was compared with that in normal tissues, P<0.05(P_g = 0.030)

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