Table 1 Univariate and multivariate analyses of factors related to survival in patients with RCC
Parameters | Univariate analysis hazard ratio (95% CI) | P value | Multivariate analysis, hazard ratio (95% CI)* | P value | ||
|---|---|---|---|---|---|---|
Relapse free survival | ||||||
T stage | ||||||
 T3 + T4/T1 + T2 | 2.97 (1.38–6.39) | 0.005 | 1.31 (0.45–3.68) | 0.607 | ||
N stage | ||||||
 N1/N0 | 1.74 (0.79–3.83) | 0.170 | 1.32 (0.82–2.11) | 0.248 | ||
M stage | ||||||
 M1/M0 | 1.85 (0.55–6.16) | 0.319 |  |  | ||
Grade | ||||||
 3 + 4/1 + 2 | 2.55 (1.41–4.62) | 0.002 | 1.46 (1.05–2.04) | 0.026 | ||
UISS category | ||||||
 High + moderate/low risk | 2.46 (1.44–4.21) | 0.001 | 2.31 (1.11–4.83) | 0.026 | ||
SNHG4 | ||||||
 High/low | 2.33 (1.13–4.83) | 0.022 | 1.77 (1.04–3.01) | 0.035 | ||
Overall survival | ||||||
T stage | ||||||
 T3 + T4/T1 + T2 | 2.42 (1.43–4.10) | 0.001 | 1.53 (1.03–2.28) | 0.037 | ||
N stage | ||||||
 N1/N0 | 2.50 (1.09–5.72) | 0.030 | 1.63 (0.88–3.03) | 0.122 | ||
M stage | ||||||
 M1/M0 | 1.65 (0.38–7.13) | 0.499 |  |  | ||
Grade | ||||||
 3 + 4/1 + 2 | 2.26 (1.39–3.67) | < 0.001 | 2.12 (0.73–6.22) | 0.170 | ||
UISS category | ||||||
 High + moderate/low risk | 2.17 (1.37–3.44) | 0.001 | 1.95 (1.07–3.55) | 0.029 | ||
SNHG4 expression | ||||||
 High/low | 3.24 (1.44–7.30) | 0.005 | 2.48 (1.02–6.03) | 0.045 | ||