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Fig. 2 | Cancer Cell International

Fig. 2

From: Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT

Fig. 2

Plumbagin inhibited the migration of BCa cells by EMT suppression. a The expression levels of β-Catenin, Vimentin, MMP9, Slug and ZO-1 protein determined by western blotting assay when T24 and UMUC3 cells were treated with plumbagin at 0, 0.75, 1.5 μM. GAPDH was used as the internal control; b The anti-migration activity of plumbagin for UMUC3 cells was further evaluated by using wound healing assay; c Representative images of migrated BCa cells (T24 and UMUC3) after plumbagin treatment; d Quantitative analysis of wound healing assay for UMUC3 cells; Quantitative analysis of T24 e and UMUC3 (f) after plumbagin treatment for transwell assay. ***P < 0.001

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