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Table 2 Different strategies for the combination of rutoside and MB-PDT

From: Molecular interaction and cellular studies on combination photodynamic therapy with rutoside for melanoma A375 cancer cells: an in vitro study

Different strategies

Pre-treatment/time

Treatment

Post-treatment/time

Cell lines

Pretreatment with rutoside for 4 h then MB-PDT

Rutoside—4 h

MB-PDT

–

A375 melanoma and HDF

Pretreatment with rutoside for 24 h then MB-PDT

Rutoside—24 h

MB-PDT

–

A375 melanoma

MB-PDT then post treatment with rutoside for 4 h

–

MB-PDT

Rutoside-4 h

A375 melanoma

MB-PDT then post treatment with rutoside for 24 h

–

MB-PDT

Rutoside-24 h

A375 melanoma

Simultaneous MB and rutoside for 1 h then PDT

–

Rutoside and MB for 1 h then PDT

–

A375 melanoma