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Fig. 1 | Cancer Cell International

Fig. 1

From: Circ0120816 acts as an oncogene of esophageal squamous cell carcinoma by inhibiting miR-1305 and releasing TXNRD1

Fig. 1

The identification of circ0120816/miR-1305/TXNRD1 axis in ESCC. a Microarray analysis revealed the top 5 upregulated circRNAs in circRNA microarray GSE131969. bf RT-qPCR analysis showed the expression of the top 5 upregulated circRNAs in ESCC clinical samples. g The structure of circ0120816. h A total of 72 upregulated DEGs were overlapped in datasets of GSE33810 and GSE20347 using Venny 2.1.0 analysis. i TXNRD1 was the key gene involved in cell population proliferation. j Eight miRNAs were identified to be overlapped using TargetScan and circInteractome analyses. TargetScan was utilized to predict miRNAs binding to TXNRD1. CircInteractome was employed to predict miRNAs binding to circ0120816

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