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Fig. 2 | Cancer Cell International

Fig. 2

From: Circ0120816 acts as an oncogene of esophageal squamous cell carcinoma by inhibiting miR-1305 and releasing TXNRD1

Fig. 2

Circ0120816 was upregulated in ESCC cells. a The receiver operating characteristic (ROC) curve showed the diagnostic value of circ0120816 for ESCC. The ROC curve was determined based on the circ0120816 expression in ESCC tissues and adjacent normal tissues. b RT-qPCR analysis revealed the expression of circ0120816 in ESCC cell lines (KYSE30, KYSE180, KYSE450, KYSE510) and normal cells (Het-1A). *P < 0.05, **P < 0.001, compared with Het-1A cells. c RNase R degradation assay confirmed the stability of circ0120816. **P < 0.001, the comparison between RNase R- and RNase R + . d The distribution of circ0120816 and linear 0120816 in ESCC cells was determined by circRNA subcellular localization assay. **P < 0.001, the comparison between the cytoplasm and the nucleus. Each cellular experiment was independently repeated three times, and the data collected were displayed in the format of mean ± standard deviation (SD)

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Cancer Cell International

ISSN: 1475-2867

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