Fig. 5

Silencing circ0120816 could inhibit the tumor growth and lung metastasis of ESCC in vivo. a Representative live imaging of xenograft mice with transplantation of KYSE450 cells lines pre-transfected with circ0120816 shRNA (Sh-circ) or negative control (NC) at week 1 and week 4. b Statistical analysis of the live imaging results. c RT-qPCR analysis of circ0120816 expression in the tumor tissues of xenograft mice. d RT-qPCR analysis of miR-1305 expression in the tumor tissues of xenograft mice. e Pathological H&E staining of tumor tissues collected from the Sh-circ and NC group mice. f Pathological H&E staining of lung tissues collected from the Sh-circ and NC group mice. **p < 0.001 compared with the NC group