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Fig. 2 | Cancer Cell International

Fig. 2

From: EZH2 promotes the expression of LPA1 by mediating microRNA-139 promoter methylation to accelerate the development of ovarian cancer

Fig. 2

High expression pattern of EZH2 is associated with the prognosis of OC patients. a Immunohistochemical staining of EZH2 in clinical OC tissues and adjacent normal tissues (×400) (n = 69). b Survival analysis by Kaplan-Meier method. c the mRNA expression pattern of EZH2 in the OC and adjacent normal tissues as determined by RT-qPCR. d The protein expression pattern of EZH2 in the OC tissues and adjacent normal tissues as measured by Western blot analysis. e The mRNA expression pattern of EZH2 in the HO8910, SKOV3, ES2 and IOSE80 cells as determined by RT-qPCR. f The protein expression pattern of EZH2 in the HO8910, SKOV3, ES2 and IOSE80 cells as measured by Western blot analysis. *p < 0.05 vs. adjacent normal tissues or IOSE80 cells; # refers to the cell line with the highest expression pattern of EZH2. The measurement data were expressed as mean ± standard deviation. The paired-designed data was compared using the paired t-test. The one-way analysis of variance was adopted for comparison among multiple groups, followed by Tukey’s post hoc test. The experiment was conducted 3 times independently

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