miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer

Table 3 Univariate analysis of overall survival in patients with epithelial ovarian cancer

	Number	Estimate	Std. error	95% Confidence interval		P (Log Rank, Mantel-Cox)
	Number	Estimate	Std. error	Lower bound	Upper bound	P (Log Rank, Mantel-Cox)
Age						0.572
≤ 50	17	64.900	10.051	45.200	84.600
> 50	22	52.803	8.234	36.665	68.941
Chemotherapy sensitivity						0.022
CR	20	71.410	8.417	54.913	87.907
IR	19	37.313	8.808	20.048	54.577
miR-206 expression						0.043
Low	20	74.923	11.042	53.280	96.566
High	19	38.825	8.969	21.246	56.404
Subtype						0.245
LGSC	4	74.666	10.091	59.289	93.044
HGSC	35	62.623	8.678	45.613	79.632
FIGO stage						0.016
I	2
II	3	75.500	3.889	67.877	83.123
III	32	56.921	7.655	41.917	71.925
IV	2	12.500	8.500	0.000	29.160

FIGO stage, International Federation of Gynecology and Obstetrics stage; HGSC, high grade serous carcinoma; LGSC, low grade serous carcinoma; CR, complete response; IR, incomplete response; P, P-value
The Ps set in italics considered statistically significant at < 0.05

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