Fig. 2
From: LncRNA LEF1-AS1 promotes metastasis of prostatic carcinoma via the Wnt/β-catenin pathway
LEF1-AS1 promotes AIPC cell proliferation, migration and invasion in vitro and in vivo. a Colony formation and EDU assay results suggested that LEF1-AS1 overexpression can promote PC3 cell proliferation, while LEF1-AS1 knockdown could inhibit DU145 cell proliferation.*P < 0.05; scale bars: 20 μm. b LEF1-AS1 promoted the migratory and invasive abilities of AIPC cells. c The neovascularization rate was notably increased after transfection with the LEF1-AS1 overexpression plasmid and decreased after transfection with siLEF1-AS1. *P < 0.05. d Tumour growth was significantly decreased in the siLEF1-AS1 group in vivo. *P < 0.05