Table 1 The characteristics of included studies
Study/Year | Country | Cancer site | Study design | Sample | Age(years) | Gender ratio | Cutoff value | Treatment | Outcome | Analysis | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|
Kushiyama et al. [19] | Japan | GC | R | 348 | Mean 79.6 ± 3.8 | 230/118 | 92 | With-surgery | Complications | M | 8 |
Migita et al. [20] | Japan | ESCC | R | 137 | — | 116/21 | 98 | With-surgery | OS, RFS | U and M | 7 |
Yamana et al. [21] | Japan | ESCC | R | 216 | — | — | 92 | With-surgery | OS | M | 8 |
Kubo et al. [14] | Japan | ESCC | R | 244 | Mean 63.4 | 196/44 | 92 | With-surgery | OS, CSS | M | 8 |
Hirahara et al. [22] | Japan | GC | R | 303 | ≥ 65 | 209/94 | 85.7 | With-surgery | Complications, OS | M | 8 |
Hu et al. [23] | China | PDAC | R | 282 | Mean 58.7 ± 13.5 | 117/165 | 98 | With-surgery | OS | M | 8 |
Iguchi et al. [24] | Japan | CRLM | R | 80 | Mean 63.6(30–86) | 44/36 | 98 | Mix | OS, RFS | M | 8 |
Sasaki et al. [25] | Japan | CRC | R | 313 | Median 73(65–94) | 201/112 | 98 | With-surgery | Complications, OS | M | 8 |
Tang et al. [10] | China | CRC | R | 230 | Mean 70.6 ± 5.4 | 154/76 | 98 | With-surgery | Complications, OS, DFS | M | 8 |