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Table 2 Stratification analysis of the meta-analysis for overall survival in patients with gastrointestinal malignancy

From: Geriatric nutritional risk index as a predictor of complications and long-term outcomes in patients with gastrointestinal malignancy: a systematic review and meta-analysis

Subgroup No. study No. patients Pooled HR (95% CI) p p for subgroup difference Heterogeneity
I2(%) PQ
Altogether 8 1805 1.94(1.65–2.28)  < 0.001   0.0 0.851
Publishing time      0.753   
 < 2019 2 353 2.04(1.44–2.88)  < 0.001   0.0 0.898
 ≥ 2019 6 1452 1.91(1.59–2.30)  < 0.001   0.0 0.665
Country      0.351   
China 2 512 1.79(1.41–2.26)  < 0.001   0.0 0.836
Japan 6 1293 2.09(1.66–2.62)  < 0.001   0.0 0.787
Sample      0.175   
 < 300 5 1295 1.84(1.53–2.20)  < 0.001   0.0 0.967
 ≥ 300 3 510 2.46(1.68–3.61)  < 0.001   0.0 0.623
Cutoff value      0.873   
 < 98 3 763 1.90(1.42–2.54)  < 0.001   0.0 0.831
 ≥ 98 5 1042 1.96(1.60–2.38)  < 0.001   0.0 0.567
Cancer site      0.673   
ESCC 3 597 1.91(1.44–2.53)  < 0.001   0.0 0.821
GC 1 303 2.09(1.11–3.96) 0.023  
PDAC 1 282 1.76(1.32–2.34)  < 0.001  
CRLM 1 80 3.72(1.41–9.85) 0.008  
CRC 2 543 2.04(1.47–2.83)  < 0.001   0.0 0.437
Primary therapy      0.181   
With-surgery 7 1725 1.90(1.61–2.24)  < 0.001   0.0 0.956
Mixed 1 80 3.72(1.41–9.85)