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Fig. 4 | Cancer Cell International

Fig. 4

From: FOXM1 modulates docetaxel resistance in prostate cancer by regulating KIF20A

Fig. 4

FOXM1 and KIF20A are consistently expressed in PCa. a Protein expression of FOXM1 and KIF20A in resistant and parental cells was analyzed using WB. b VCaP, DU145, and their respective resistant cell variants were treated with different doses of DOC (0 μM, 5 μM, 10 μM, 20 μM). WB was performed to assess protein levels of FOXM1 and KIF20A in the presence and absence of DOC. Quantitative analysis was performed using the Gel-Pro 32 software. c FOXM1 and KIF20A mRNA expression levels were analyzed in either 492 prostate cancer tumor tissues or 52 normal prostate tissues using TCGA data. d Correlation analysis was used to analyze the correlation in expression of FOXM1 and KIF20A in prostate cancer tissues in the TCGA database. *p < 0.05

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