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Table 1 External Validation of Biomarkers in SARC via Multiple Online Database

From: Targeting Lymphotoxin Beta and Paired Box 5: a potential therapeutic strategy for soft tissue sarcoma metastasis

  PAX5 LTB (anti-oncogene) IL1A (anti-oncogene) IL5RA (anti-oncogene) IL7 (anti-oncogene) LY9 (anti-oncogene) SLAMF7 (anti-oncogene) ICAM1 (anti-oncogene)
Oncomine Expression: NA Expression: Low Expression: NA Expression: High Expression: NA Expression: Low Expression: Low Expression: Low
UALCAN Expression: NA
Survival: P = 0.290
Expression: P < 0.001
Survival: P = 0.006
Expression: P < 0.001
Survival: P = 0.019
Expression: P = 0.781
Survival: P = 0.031
Expression: 0.471
Survival: P = 0.041
Expression: P < 0.001
Survival: P = 0.008
Expression: P < 0.001
Survival: P = 0.013
Expression: P = 0.521
Survival: P = 0.030
K-M Plotter Survival: P = 0.084 Survival: P < 0.001 Survival: P = 0.003 Survival: P < 0.001 Survival: P = 0.010 Survival: P < 0.001 Survival: P = 0.006 Survival: P = 0.015
GEPIA Survival: P = 0.380
Correlation: P < 0.001
R = 0.34
Survival: P = 0.004 Survival: P = 0.056
Correlation: P = 0.016
R = 0.15
Survival: P < 0.001
Correlation: P < 0.001
R = 0.41
Survival: P = 0.120
Correlation: P < 0.001
R = 0.50
Survival: P = 0.006
Correlation: P < 0.001
R = 0.81
Survival: P = 0.078
Correlation: P < 0.001
R = 0.79
Survival: P = 0.037
Correlation: P < 0.001
R = 0.56
LinkedOmics Survival: P = 0.500
Correlation: P < 0.001
R = 0.31
Survival: P < 0.001 Survival: P = 0.015
Correlation: P = 0.008
R = 0.17
Survival: P = 0.030
Correlation: P < 0.001
R = 0.43
Survival: P = 0.022
Correlation: P < 0.001
R = 0.51
Survival: P = 0.001
Correlation: P < 0.001
R = 0.82
Survival: P = 0.008
Correlation: P < 0.001
R = 0.79
Survival: P = 0.035
Correlation: P < 0.001
R = 0.61
TISIDB Survival: NA Survival: P = 0.006 Survival: P = 0.019 Survival: NA Survival: P = 0.021 Survival: P < 0.001 Survival: P = 0.006 Survival: P = 0.043
cBioportal Correlation: P < 0.001
R = 0.31
  Correlation: P = 0.009
R = 0.16
Correlation: P < 0.001
R = 0.43
Correlation: P < 0.001
R = 0.52
Correlation: P < 0.001
R = 0.83
Correlation: P < 0.001
R = 0.79
Correlation: P < 0.001
R = 0.60
  1. PAX5: Paired Box 5; LTB: Lymphotoxin Beta; IL1A: Interleukin 1 Alpha; IL5RA: Interleukin 5 Receptor Subunit Alpha; IL7: Interleukin 7; LY9: Lymphocyte Antigen 9; SLAMF7: Signaling Lymphocytic Activation Molecule Family Member 7; ICAM1: Intercellular Adhesion Molecule 1